AGE-RELATED CHANGES IN RAT LIVER HYDRATION AND HISTOSTRUCTURE

One of the aging hypotheses is based on fact that percentage water in human body decreases with age. To a greater extent, loss affects most energy-dependent organs, such as liver, which undergoes number structural compensatory-adaptive changes. The parameters age-related changes are currently understudied. However, they should be taken into account when determining actual organ transformations experiments.
 purpose study was to examine change level total and liver histostructure rats during 75-day observation.
 Materials Methods. parenchyma were assessed young outbred intact observation. authors examined sections stained hematoxylin-eosin picrofuchsin (Van Gieson's stain).
 Results. A decrease rat by 0.54±0.042 % observed At same time, no visible detected histostructure.
 Conclusion. During trial animals observed. It did not affect histostructure.